HomeRoutesMIA → EZE → SCL → LIM
Multi-City Itinerary · Latin America
MIAEZESCLLIM

Miami → Buenos Aires → Santiago → Lima

The South America Circuit

Total flying~15h flying
Stops4 cities
From$3,900
Best seasonApr–Oct
AirlinesAmerican Airlines, LATAM Airlines

Full Itinerary

MIA
Miami
~9h
EZE
Buenos Aires3 nights
~2h 30m
SCL
Santiago3 nights
~3h 30m
LIM
Lima3 nights

Multi-city pricing advantage

From $3,900 per person in business class

Save ~$1,600–$2,400 vs. three separate return fares

Savings estimates are based on published business class fare comparisons vs. equivalent separate return fares. Actual savings vary by booking date and availability. Our specialists advise on the exact fare combination.

Why travel Miami to Lima?

Miami to Buenos Aires, Santiago, and Lima is the most comprehensive South American premium itinerary — covering Argentina's cultural sophistication, Chile's Andean scenery, and Peru's extraordinary Inca heritage in a single logical progression. The routing northward from Buenos Aires through Santiago to Lima means you're always moving toward your return gateway.

Why book as a multi-city itinerary?

The MIA–EZE outbound / LIM–MIA homebound open-jaw is the defining structure for this itinerary. LATAM operates the widest network of intra-South American connections and their business class product has improved significantly since the post-pandemic relaunch. Our specialists construct the combined fare across American Airlines and LATAM, typically saving $1,600–$2,400 vs. three separate returns.

Premium cabin options by segment

MIA → EZE
American Airlines / LATAMFlagship Business / Business Class

Overnight crossing; American Flagship Business on 777 with fully flat beds

EZE → SCL
LATAM AirlinesBusiness Class

2h30 Andes crossing; LATAM's LATAM Plus Business on this route

SCL → LIM
LATAM AirlinesBusiness Class

3h30 Pacific Coast crossing; LATAM operates the highest frequency between South American capitals

This multi-city itinerary requires careful fare construction to unlock the best pricing. Our specialists identify the correct open-jaw fare combination, cabin configuration, and booking sequence to maximise value.

Planning tips for this itinerary

Buenos Aires (3–4 nights, Recoleta and Palermo), Santiago (3 nights, use as base for day trips to the Atacama or Patagonia trekking), and Lima (3–4 nights, Miraflores, Barranco, and Machu Picchu access via Cusco). April–October is South America's shoulder/winter season, with prices significantly lower than December–February. Book Machu Picchu train tickets (IncaRail or PeruRail) well ahead — they regularly sell out 3–4 months in advance.

Why use MulticityExperts for this route?

We construct the open-jaw fare combination that airlines' booking engines deliberately obscure.

We compare premium cabin availability across all carriers on every segment simultaneously.

We advise on surface transport alternatives (rail, ferry) that may save time and money.

You speak to a real specialist who has personally planned itineraries on this routing.

Frequently asked questions

How It Works

Our Concierge Process

01

Share Your Journey

Tell us your destinations, dates, and preferences. No forms, just a conversation with a dedicated specialist.

02

Receive Curated Options

Your specialist presents tailored flight combinations optimised for schedule, comfort, and value, within 24 hours.

03

Confirm & Travel

We handle ticketing, seat selection, and every detail. Travel confidently knowing your specialist monitors the journey.

Ready to plan this journey?

Our specialists will find the best open-jaw fare combination, compare every premium cabin on this route, and build a detailed itinerary tailored to your travel dates.